The following section explains some issues unique to Maya for Mac OS X, and suggests workarounds.
If you have a folder in your /Users/username/Documents/maya/projects folder that has a bullet character (option 8) in its name, Maya will not retain the project as it is set. It will return to the default the next time Maya is run.
Remove the problem folder or rename it and restart Maya.
If you are using a dual monitor setup, the marking menus and hotbox only work on the main monitor.
You can turn off separate workspaces on the Mac OS X platform by selecting System Preferences, then selecting Mission Control, then disabling Displays have Separate Spaces.