You can temporarily disable the evaluation of problematic nodes by the Evaluation Manager. Problematic nodes create playback slowdowns, and disabling them can increase performance. This way, you can evaluate things that are necessary to a scene.
You can use the Profiler to identify which nodes are causing slowdowns. See Locate animation bottlenecks with the Profiler.
To exclude a node from evaluation
This turns off the evaluation of the selected node.
See the Evaluation Toolkit for more tools to increase scene performance.