Use clusters when you want to affect different parts of geometry in different amounts during transformations. For example, you can create a cluster for a door so that when it is slammed, the middle bows slightly.
Cluster deformers let you control a set of points on the object (CVs, vertices, or lattice points) with varying amounts of influence. The deformer applies transformations to the points in a way that lets you adjust the precise percentage that each point is affected.
A cluster deformer creates a set whose members consist of selected points (CVs, vertices, or lattice points). You can assign a percentage weight to each point, indicating how much you want each point to be affected by any translation, rotation, or scaling of the cluster set. When you transform the cluster, the points are transformed according to the percentages you specify.