Use the Wire Layer/Format Overrides tool to have wire numbering automatically insert with wire color, gauge, and type information encoded into the wire number itself.

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The Assign Wire Numbering Formats by Wire Layers dialog box opens. Enter each wire layer name and the wire number format that you want to see for wire numbers on that wire layer. For example, let's say that you routinely use wire layers "RED_14_THHN" and "BLK_10_XHHN" in drawings in your project. Whenever you have a wire number on the red wire, you want AutoCAD Electrical toolset to append a "-RD-14" suffix automatically to the wire number. For wire numbers generated on wires drawn on layer BLK_10_XHHN, you want AutoCAD Electrical toolset to append a "-BLK-10" suffix to the wire number automatically.
This information is stored in the project's .wdp file and is applied across all drawings listed in your project.
Now when you run the Insert Wire Numbers command on any drawing in your project, nonfixed wire numbers update if they are associated with wires that are tagged in your override list.