Orthographic drawings are best managed by creating a master model from which the orthographic drawing will be extracted. It is created in the same way as the Area Master model. The appropriate Area Master models are Xref'd and then the layers are managed in order to show the required components on the final drawing. 
Using the Ortho Master, the ortho extraction process can be performed and once completed, the final drawing and ortho master are saved. Now updates to the drawings can be made easily, through the master or by updating the ortho drawing view. 
The above process may look like we will have many files to manage, and this may be true. But by managing them in this way, drawings can be created at any time, even while modeling is going on and then drawings can be updated consistently.