The Knowledge Vault Master is moved by relocating the corresponding mdf, LDF files from their existing location to another location on the same computer.
The default path for the database files for KVM is C:\Program Files\Microsoft SQL Server\MSSQL10_50.AUTODESKVAULT\MSSQL\DATA.
Select Tools >Move Master Vault.
On the Move Database Files dialog browse to the new location for the Data file (mdf) and Log file (LDF).
Click OK on the browse dialog.
Click OK on Move Database Files dialog.
Select Yes on the prompt to proceed with the Move operation.