It is recommended that you use a Wacom® pen tablet in order to take full advantage of Mudbox sculpting features. However, you can sculpt in Mudbox using a standard three-button mouse.
You can also operate Mudbox using gestural input if you have a multi-touch device. See Multi-Touch devices.
The most current software drivers for Wacom® tablets are available here:
http://www.wacom.com/productsupport/select.cfm
Note: The Wacom web site provides worldwide download links.